abstract：:Tumor tissue from a patient with squamous cell carcinoma of the lung and hypercalcemia has been serially implanted into athymic mice. Tumor-bearing mice develop cachexia, hypercalcemia without bone metastases, hypophosphatemia, increased urinary cyclic adenosine monophosphate (cAMP) to creatinine ratio, and undetectab...

journal_title：Calcified tissue international

authors： Abramson EC,Kukla LJ,Shevrin DH,Lad TE,McGuire WP,Kukreja SC

更新日期：1984-09-01 00:00:00

abstract：:The present study examined calcium phosphate precipitation in aqueous suspensions of multilamellar liposomes as a possible in vitro model for matrix vesicle mineralization. Liposomes were prepared by dispersing CHCl3-evaporated thin films of 7:2:1 and 7:1:1 molar mixtures of phosphatidylcholine, dicetyl phosphate, and...

journal_title：Calcified tissue international

authors： Eanes ED,Hailer AW,Costa JL

更新日期：1984-07-01 00:00:00

abstract：:The existence of nutritional deficiency rickets among infants in sunny Riyadh was confirmed radiologically. Most of the rachitic infants were breast-fed, some received unsupplemented infant feeding formulae, and all live in an environment that is devoid of sunlight. Their mean age at the time of onset was 10.5 months....

journal_title：Calcified tissue international

authors： Elidrissy AT,Sedrani SH,Lawson DE

更新日期：1984-05-01 00:00:00

abstract：:The influence of gastric acidity on the absorption of intragastrically administered fluoride was investigated in rats. Intact animals were pretreated with atropine or cimetidine to reduce gastric acid secretion or were given fluoride in NaHCO3 to reduce the acidity of the gastric contents. Compared with pentagastrin-t...

journal_title：Calcified tissue international

authors： Whitford GM,Pashley DH

更新日期：1984-05-01 00:00:00

abstract：:Using a histochemical method for demonstrating acid phosphatase activity, we have studied osteoclasts residing at two different bone sites in rat incisor alveolar bone, one at the endosteum and the other at the tooth socket, and compared the response of these osteoclasts to systemic changes. After 12 days of calcium (...

journal_title：Calcified tissue international

authors： Liu CC,Baylink DJ

更新日期：1984-03-01 00:00:00

abstract：:The severest long-term complications of orthopedic joint-prostheses are associated with loosening of the implant-bone interface, due to adverse reactions in bone and subsequent weakening of the connection between the two materials. Mechanical stresses, caused by joint loading, play a key role in the adaption of interf...

journal_title：Calcified tissue international

authors： Huiskes R,Nunamaker D

更新日期：1984-01-01 00:00:00

abstract：:Cortical bone can be modeled as a complex hierarchical composite interrelating both structure and material properties on four levels of structural organization: molecular, ultrastructural, microscopic, and macroscopic. In young animals, the microstructural systems are long parallel lamellar units, plexiform bone, whic...

journal_title：Calcified tissue international

authors： Katz JL,Yoon HS,Lipson S,Maharidge R,Meunier A,Christel P

更新日期：1984-01-01 00:00:00

abstract：:The ability of 1,25(OH)2D3 and of 24,25(OH)2D3 to prevent or to heal rickets in chicks was evaluated by studies of plasma biochemistry, growth plate histology, bone morphometry and microradiography, and bone mineralization. 1,25(OH)2D3 at a dose of 100 ng/day produced fewest abnormalities compared with vitamin D3-trea...

journal_title：Calcified tissue international

authors： Dickson IR,Hall AK,Jande SS

更新日期：1984-01-01 00:00:00

abstract：:Vit-D-Dependent calcium binding protein and parvalbumin have both been detected in ameloblasts and calcified cartilage by immunohistochemical techniques. These two Ca2+ binding proteins may play a crucial role in the local accumulation of Ca2+ ions during the process of mineralization. The mechanisms underlying the de...

journal_title：Calcified tissue international

authors： Celio MR,Norman AW,Heizmann CW

更新日期：1984-01-01 00:00:00

abstract：:Dual-photon absorptiometry (153Gd) was used to measure bone mineral of the total body and major anatomical areas. Patients with osteoporosis (male = 11, female = 18) and with renal osteodystrophy (n = 17) were significantly below (20%) normal females (n = 72) and males (n = 13) at most sites. In the osteoporotic patie...

journal_title：Calcified tissue international

authors： Mazess RB,Peppler WW,Chesney RW,Lange TA,Lindgren U,Smith E Jr

更新日期：1984-01-01 00:00:00

abstract：:The effect of magnesium (Mg) supplementation on bone metabolism has been studied in the normal young mouse. Weanling male mice were given Mg-supplemented drinking water (5 mM or 32 mM Mg) for 4 weeks. Mineral and skeletal changes were assessed by biochemical methods and by histomorphometric analysis of endosteal bone ...

journal_title：Calcified tissue international

authors： Marie PJ,Travers R,Delvin EE

更新日期：1983-09-01 00:00:00

abstract：:The increased uptake of bone-seeking radionuclides following a fracture has been stated to be due to an increase in bone blood flow, resulting in an increase in capillary surface area available for exchange. This paper examines the relationship between the maximum instantaneous extraction of 99mTc-MDP and blood flow i...

journal_title：Calcified tissue international

authors： McCarthy ID,Hughes SP

更新日期：1983-07-01 00:00:00

abstract：:We separated osteoclasts from bone and observed the effect of several known and potential mediators of the control of bone resorption on their cytoplasmic motility. We already found that calcitonin (CT), a hormone that inhibits bone resorption, regularly causes complete inhibition of cytoplasmic motility, specific for...

journal_title：Calcified tissue international

authors： Chambers TJ,Dunn CJ

更新日期：1983-07-01 00:00:00

abstract：:Forty 5-week-old rats were randomly divided into 1 control group given a normal diet and water low in fluoride (0.026 mM/1) and experimental group receiving the same basic diet and a fluoride supplement of 2.6 mMol/l in the drinking water. After 30 weeks, half of the fluoride-supplemented and half of the nonsupplement...

journal_title：Calcified tissue international

authors： Rosenquist JB,Lorentzon PR,Boquist LL

更新日期：1983-07-01 00:00:00

abstract：:The binding of prostaglandin E2 (PGE2) to bone cells was studied to provide direct evidence for the existence of specific receptors in bone. Bone cells were isolated by collagenase digestion of fetal and newborn rat calvaria. Isolated cells were incubated with 3H-PGE2 and collected on Millipore filters. Specific bindi...

journal_title：Calcified tissue international

authors： Dziak RM,Hurd D,Miyasaki KT,Brown M,Weinfeld N,Hausmann E

更新日期：1983-01-01 00:00:00

abstract：:A whole-body counter was used to measure the retention and distribution of radioactivity along the longitudinal axis of the body during 10 days after the intravenous injection of 50 microCi of 47Ca. These data and the simultaneous measurements of the serum specific activity allowed us to calculate, by the Bauer-Carlss...

journal_title：Calcified tissue international

authors： Bergmann P,Paternot T,Schoutens A

更新日期：1983-01-01 00:00:00

abstract：:The crystallinity of bone mineral at different stages of maturation has been measured by quantitative X-ray diffraction methods. Crystallinity measurements were made on tibial mid-diaphyses from 17-day embryonic chicks, newly-formed periosteal bone from embryonic chicks, and density-fractionated bone from post-hatch c...

journal_title：Calcified tissue international

authors： Bonar LC,Roufosse AH,Sabine WK,Grynpas MD,Glimcher MJ

更新日期：1983-01-01 00:00:00

abstract：:Whole enamel scrapings from unerupted teeth of embryonic calves have been separated into fractions of varying density by stepwise centrifugation in bromoform-toluene mixtures of increasing specific gravity. Partition of enamel in this manner yields individual fractions of increasing mineral phase age and maturation. W...

journal_title：Calcified tissue international

authors： Landis WJ,Navarro M

更新日期：1983-01-01 00:00:00

abstract：:Unfixed, undecalcified sections from closed fractures of rat metatarsals have been studied by quantitative cytochemistry from the first week after fracture to late in the fracture-healing process. Alkaline phosphatase activity appeared to be related to calcification. Glucose 6-phosphate dehydrogenase activity was asso...

journal_title：Calcified tissue international

authors： Dunham J,Catterall A,Bitensky L,Chayen J

更新日期：1983-01-01 00:00:00

abstract：:Each of the presently available noninvasive methods used to determine the nature and degree of changes in skeletal mass has significant advantages and limitations. Dual photon absorptiometric techniques generally have a very low radiation dose. They are also less expensive to construct than other systems. However, the...

journal_title：Calcified tissue international

authors： Cohn SH

更新日期：1982-09-01 00:00:00

abstract：:It has recently been demonstrated that calcium ionophore A23187 mimics certain of the effects of parathyroid hormone (PTH) on bone in vitro, including stimulation of 45Ca release and cAMP formation. To further examine the relative effects of these two agents on bone cell metabolism, we compared the effects of syntheti...

journal_title：Calcified tissue international

authors： DeBartolo TF,Pegg LE,Shasserre C,Hahn TJ

更新日期：1982-09-01 00:00:00

abstract：:We have compared two components of bacterial cell walls, muramyl dipeptide (MDP) and lipopolysaccharide (LPS), for their effects on bone resorption as measured by the release of previously incorporated 45Ca. MDP is the smallest active component of peptidoglycan, whereas LPS is the active component of endotoxin. Fetal ...

journal_title：Calcified tissue international

authors： Raisz LG,Alander C,Eilon G,Whitehead SP,Nuki K

更新日期：1982-07-01 00:00:00

abstract：:Formalin fixation of hard tissues alters the levels of some, but not all, of the parameters routinely measured by bone researchers. Although mineral parameters (ash weight, particle size (beta 1/2 002) and Ca/PO4 ratio) and lipid parameters (total lipid content and composition, extractability, and Ca-acidic phospholip...

journal_title：Calcified tissue international

authors： Boskey AL,Cohen ML,Bullough PG

更新日期：1982-07-01 00:00:00

abstract：:A continuous flow organ culture system (CFCS) was used to determine the effect of ascorbic acid on the synthesis of collagen and noncollagenous protein by bone of the alveolar process and periodontal ligament in organ cultures of adult mouse periodontium. For the last 24 h of 2 day cultures, 5 microCi/ml 3H-proline wa...

journal_title：Calcified tissue international

authors： Sodek J,Feng J,Yen EH,Melcher AH

更新日期：1982-07-01 00:00:00

abstract：:The hypophosphatemic male mouse (Hyp/y), the proposed model for human vitamin D-resistant rickets (VDRR), is characterized by chronic hypophosphatemia, dwarfism, and rachitic and osteomalacic bone lesions. We have reported that treatment of Hyp/y mice with phosphate salts (Pi) heals rickets but does not correct the de...

journal_title：Calcified tissue international

authors： Marie PJ,Travers R,Glorieux FH

更新日期：1982-03-01 00:00:00

abstract：:Recent evidence of the occurrence of brushite in newly formed bone mineral prompted a study of the solubility properties of brushite:apatite mixtures under physiological conditions and the influence on them of pH, lactate, pyruvate, and, particularly, noncollagenous bone proteins (NCBPs). Brushite alone was surprising...

journal_title：Calcified tissue international

authors： Neuman WF,Neuman MW,Diamond AG,Menanteau J,Gibbons WS

更新日期：1982-03-01 00:00:00

abstract：:Calcium-acidic phospholipid-phosphate complexes (Ca-PL-PO4) cause hydroxyapatite (HA) deposition in vitro. The acidic phospholipids--phosphatidylserine (PS), phosphatidylinositol (PI), phosphatidylglycerol (PG), and diphosphatidylglycerol (DPG)--all form Ca-PL-PO4 complexes: Nonacidic phospholipids--sphingomyelin (SPL...

journal_title：Calcified tissue international

authors： Boskey AL,Posner AS

更新日期：1982-01-01 00:00:00

abstract：:Although radiogenic free radicals are widely used as molecular probes in biological calcified tissues, their nature and their location remain controversial. In the present study we have synthesized and irradiated apatites in which 13CO3(2-) ions substitute hydroxyl or phosphate ions in hydroxyapatite. The 13C-coupling...

journal_title：Calcified tissue international

authors： Geoffroy M,Tochon-Danguy HJ

更新日期：1982-01-01 00:00:00

abstract：:The bone mineral status of 17 girls with Turner's syndrome was evaluated by single photon absorptiometry. Bone mineral content (BMC) was 25.4% below that predicted by normalization for age, sex, height, weight, and bone width. Only 25% of this demineralization could be attributed to delayed skeletal maturation. Bones ...

journal_title：Calcified tissue international

authors： Shore RM,Chesney RW,Mazess RB,Rose PG,Bargman GJ

更新日期：1982-01-01 00:00:00

abstract：:Using both low microwave power and weak magnetic field modulation, we have shown that the asymmetric signal arising in X-irradiated tooth enamel as well as in A-type carbonated apatite exposed to X-rays or to excited oxygen has an orthorhombic character and must be attributed to CO2-. Effectively, the mean values foun...

journal_title：Calcified tissue international

authors： Bacquet G,Truong VQ,Vignoles M,Trombe JC,Bonel G

更新日期：1981-01-01 00:00:00

abstract：:Vitamin D3 deficient (D-) mice show a depressed inflammatory response and both inflammatory peritoneal macrophages and bone marrow polymorphonuclear leukocytes of D- mice exhibit a decreased spontaneous migration under agarose. The impaired phagocytic response of peritoneal macrophages from D- mice can be corrected by...

journal_title：Calcified tissue international

authors： Bar-Shavit Z,Noff D,Edelstein S,Meyer M,Shibolet S,Goldman R

更新日期：1981-01-01 00:00:00

abstract：:The effects of fluoride on human enamel and selachian enameloid in vitro were visualized in TEM and analyzed with electron diffraction. It is demonstrated that under precise pH conditions, inducing concentration balance between F-ions and apatite, calcium fluoride is no longer formed, and crystalline changes occur ins...

journal_title：Calcified tissue international

authors： Daculsi G,Kerebel LM,Kerebel B

更新日期：1981-01-01 00:00:00

abstract：:This report describes a method using direct photon absorptiometry (DPA) for determination in vivo of the bone mineral content to bone width ratio (BMC/W) in the rat femur. A significant correlation was noted between measurements by DPA and whole femur dry weight and ash weight. Measurements were reproducible within re...

journal_title：Calcified tissue international

authors： Sanchez TV,Myers RC,Bond JT,Mayor GH

更新日期：1981-01-01 00:00:00

abstract：:Inoculation of Moloney murine sarcoma virus (M-MSV) into shank muscles of adult NMRI mice resulted in localized sarcoma and periosteal membrane proliferation with subsequent periosteal bone formation. Newly formed bone arose from outer surface of shank bones. Two weeks after M-MSV inoculation the width of bone cortex ...

journal_title：Calcified tissue international

authors： Włodarski K,Kobus M,Luczak M,Dołowy J

更新日期：1981-01-01 00:00:00

abstract：:Normal rat bone maturation has been studied using biochemical methods and hydrazine separation of matrix and mineral for X-ray diffraction. In the bone, the amount of mineral increases between 4 and 22 weeks of age, while in the matrix, the ratio of noncollagenous protein to collagen progressively decreases. In minera...

journal_title：Calcified tissue international

authors： Burnell JM,Teubner EJ,Miller AG

更新日期：1980-01-01 00:00:00

abstract：:The extractions of 85Sr2+, 18F-, sucrose-14C, EDTA-51Cr, and antipyrine-14C in bone were determined by the multiple indicator-dilution method. Fluoride and strontium extractions were 18 to 70% during a single transcapillary passage, and those of EDTA and sucrose were from 11 to 59%, whereas extraction of antipyrine wa...

journal_title：Calcified tissue international

authors： Lemon GJ,Davies DR,Hughes SP,Bassingthwaighte JB,Kelly PJ

更新日期：1980-01-01 00:00:00

abstract：:We compared the effects of four vitamin D metabolites, 1 alpha,25 dihydroxy vitamin D3 (1 alpha,25(OH)2D3), 1 alpha hydroxy vitamin D3 (1 alpha OH D3), 25 hydroxy vitamin D3 (25 OH D3), and 24R,25 dihydroxy vitamin D (24R,25(OH)sD3) on resorption and collagen synthesis in fetal rat bone maintained in organ culture. Re...

journal_title：Calcified tissue international

authors： Raisz LG,Kream BE,Smith MD,Simmons HA

更新日期：1980-01-01 00:00:00

abstract：:Further insight into human tooth enamel, dense fraction (TE), has been obtained by following the change and loss of CO3(2-), OH-, structurally incorporated H2O, Cl-, and, indirectly, HPO4(2-) after TE had been heated in N2 or vacuum in the range 25-1000 degrees C. Quantitative infrared spectroscopic, lattice parameter...

journal_title：Calcified tissue international

authors： Holcomb DW,Young RA

更新日期：1980-01-01 00:00:00

abstract：:The diphosphonates dichloromethanediphosphonate (Cl2MDP) and to a minor degree 1-hydroxyethane-1,1-diphosphonate (EDHP) increased the glycogen content in cultured cartilage cells of rabbit ear. This effect was not due to different concentrations of glucose in the medium. ...

journal_title：Calcified tissue international

authors： Felix R,Fast DK,Sallis JD,Fleisch H

更新日期：1980-01-01 00:00:00

abstract：:Octacalcium phosphate (Ca8H2(PO4)6 . 5H2O) is considered to be precursor in the formation of apatite in bones and teeth; a crucial step for incorporation of impurities appears to occur during its hydrolysis. The present study examines the role that octacalcium phosphate plays in the process of incorporation of carbona...

journal_title：Calcified tissue international

authors： Chickerur NS,Tung MS,Brown WE

更新日期：1980-01-01 00:00:00